Born in Palermo, Ugo Guagliardo studied singing and piano, and also philosophy. His repertoire includes standard classical as well as contemporary rôles.

He has appeared in major Italian opera houses, including Turin, Rome, Bologna and Palermo, as well as in international houses and festivals, including the Mozart festival in La Coruña, the Belcanto festival in Dordrecht and Rossini in Wildbad. He has also sung principal Rossini rôles in Paris, Geneva and Tel Aviv, and many bel canto rôles in European theatres under the baton of distinguished conductors.